Cream.Eco Plus 10mg

Indications of Ecoplus 10 Cream

Econazole Nitrate & Triamcinolone Acetonide indicated for the treatment of:

• Eczematous Mycoses
• Psoriasis
• Tinea Pedis (Athlete’s foot)
• Tinea Corporis (Ring worm)
• Tinea Cruris (Jock itch)
• Inflammatory Intertrigo
• Diaper Dermatitis

Pharmacology of Ecoplus 10 Cream

In a suitable base, Triamcinolone Acetonide (a Triamcinolone derivative). Topical steroids are used for their anti-inflammatory, anti-pruritic, and vasoconstrictive properties.

Dosage and Administration of Ecoplus 10 Cream

Adults: This cream should be applied sparingly to the skin lesion no more than 2 times daily, preferably once in the morning and once in the evening. This cream should not be applied with an occlusive dressing, or to large areas of skin on the body. The duration of treatment with this cream should continue until the inflammatory symptoms subside but not longer than 2 weeks; after 2 weeks of therapy with this cream, continue therapy as needed with a preparation containing econazole or econazole nitrate alone.

Pediatric Use: Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight. Caution should be exercised.

Interaction of Ecoplus 10 Cream

Econazole is an oral anticoagulant that is metabolized by the CYP3A4/2C9 enzyme (warfarin & acenocoumarol).

Triamcinolone reduces the amount of salicylates in the blood. NSAIDs increase the risk of Gl bleeding and ulceration. Antagonized the antidiabetic's blood glucose-lowering effects. Amphotericin B, beta-blockers, potassium-depleting diuretics, and theophylline all increase the risk of hyperkalemia. With ciclosporin, carbamazepine, phenytoin, barbiturate, and rifampicin, triamcinolone clearance is increased.

Triamcinolone Acetonide should not be applied to healthy skin or wide regions of skin, and it should not be used in the eyes because it can cause glaucoma and cataracts.

Contraindications

Patients having a history of hypersensitivity to any of the preparation's components should avoid using triamcinolone acetonide. It's also not recommended for skin TB, fungus infections, and viral skin disorders (Herpes simplex, chickenpox, and vaccinia), as well as perioral dermatitis, rosacea, and ulcerative conditions.

Side effects of Ecoplus 10 Cream

Burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis and allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria have all been reported with topical corticosteroids, either with or without occlusive dressings.

Pregnancy & Lactation

There have been no appropriate and well-controlled investigations on the teratogenic consequences of topically administered corticosteroids in pregnant women. As a result, only if the potential benefit outweighs the danger to the fetus should topical corticosteroids be administered during pregnancy. It's unclear if topical corticosteroid therapy would result in enough systemic absorption to produce measurable amounts in breast milk. Corticosteroids that are taken systemically are secreted in breast milk in amounts that are unlikely to harm the newborn. When topical corticosteroids are given to a nursing mother, however, caution should be maintained.

Precautions & Warnings

Triamcinolone Acetonide should be stopped if any reactions or peculiarities occur. Topical steroids should be used with caution and close observation on affected regions, keeping in mind the risk of infection spread from anti-inflammatory drugs and the possibility of terminating steroid therapy and/or commencing antibacterial therapies.

Triamcinolone Acetonide should not be applied to healthy skin or wide regions of skin, and it should not be used in the eyes because it can cause glaucoma and cataracts. Atrophic striae are more likely to appear when steroids are used for long periods of time (greater than 4 weeks). The use of flexures and intertriginous zones for an extended period of time is not recommended. Topical corticosteroids are absorbed at a higher rate in children, making them more susceptible to systemic harm. Long-term continuous topical steroid medication in babies should be avoided. Even without blockage, adrenal suppression can develop.

Triamcinolone Acetonide should not be applied to healthy skin or wide regions of skin, and it should not be used in the eyes because it can cause glaucoma and cataracts.

Therapeutic Class

Triamcinolone & Combined preparations

Storage Conditions

Store in a cool & dry place. Protect from light.

Pharmaceutical Name of Ecoplus 10 Cream

Team Pharmaceuticals Ltd

Generic of Ecoplus 10 Cream

Econazole Nitrate + Triamcinolone Acetonide